For USA use only
Consider FDA-approved medical therapies in postmenopausal women and men aged 50 years and older, based on the following:
- A hip or vertebral (clinical or morphometric) fracture
- T-score ≤ -2.5 at the femoral neck or spine after appropriate evaluation to exclude secondary causes
- Low bone mass (T-score between -1.0 and -2.5 at the femoral neck or spine) and a 10-year probability of a hip fracture ≥ 3% or a 10-year probability of a major osteoporosis-related fracture ≥ 20% based on the US-adapted WHO algorithm
- Clinicians judgment and/or patient preferences may indicate treatment for people with 10-year fracture probabilities above or below these levels